Inherited Metabolic Diseases by Georg F. Hoffmann Johannes Zschocke & William L. Nyhan

Author:Georg F. Hoffmann, Johannes Zschocke & William L. Nyhan
Language: eng
Format: epub
Publisher: Springer Berlin Heidelberg, Berlin, Heidelberg

7.4 Take Home Messages

Many neurometabolic diseases manifest symptoms compatible with various psychiatric diagnoses. Psychiatric features may be a leading clinical correlate of certain metabolic diseases as well as an important sequel in long-term care. With improvements in treatment and prognosis, manifestations that affect long-term quality of life such as psychiatric problems become increasingly important in an older patient population.

Recognition of metabolic diseases in the differential diagnosis of psychiatric manifestations is important since some metabolic diseases may be mistaken for diagnoses such as schizophrenia. In AIP, psychiatric symptoms may be at the forefront of clinical manifestations. Careful examination of mental and neurological status, psychiatric history, and recognition of psychotropic drugs or treatment regimens potentially exacerbating metabolic crises, e.g., in porphyrias or in Wilson disease, are mandatory.

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